Researcher: Yutaka Saito
Affiliation: School of Frontier Engineering, Kitasato University / Artificial Intelligence Research Center, The National Institute of Advanced Industrial Science and Technology
 

Abstract: Proteins are utilized as functional molecules across a wide range of fields. Their applications are countless, including antibodies used as pharmaceuticals, enzymes that produce substances or break down contaminants, and fluorescent proteins that enable visualization within living organisms. In industry, there is a broad demand for designing such proteins and enhancing their functions. Traditionally, the development of functional proteins has required large-scale trial-and-error experimentation, but in recent years, attention has been shifting toward smart design using AI. In particular, a technology known as "protein language models," which applies AI techniques behind language models like ChatGPT to the string representations of proteins, is rapidly advancing.